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EmStat Pico Core

Proven and tested dual-channel potentiostat chip

  • Attractive for high-volume applications
  • Small footprint of 5 x 6 mm
  • Use MethodSCRIPT to perform electrochemistry
  • PalmSens reference design for easy integration
  • Support from Analog Devices & PalmSens
PalmSens usually responds to your quotation request within one business day.


The EmStat Pico Core is a high-volume potentiostat chip for use with MethodSCRIPT™ that enables you to perform electrochemical measurements using your own electrochemical sensor without programming skills. You can integrate this small dual-channel chip of 5 by 6 mm on your PCB without any potentiostat knowledge thanks to the joint development by Analog Devices Inc and PalmSens. Our reference design, network, experience and support will help you succeed and save development time with the smallest potentiostat chip on the market.

  • Dimensions: 5 x 6 mm
  • Dual channel (2x WE, 2x RE, 2x CE)
  • EIS frequency range: 0.016 Hz to 200 kHz
  • Full dc-potential range: -1.7 V to +2 V
  • Current ranges: 100 nA to 5 mA
  • Four different versions available, each with different electrochemical techniques.

Advantages and Overview

The EmStat Pico Core is at the heart of the EmStat Pico Module.  There are two main advantages of the EmStat Pico Core, compared with the EmStat Pico module

  • Economical solution for high volumes
  • Smaller footprint

The EmStat Pico Core is an attractive option if you need >10k units. Lower quantities are available for prototyping. The EmStat Pico Core is distributed via PalmSens and .

Pico vs Pico Core

EmStat Pico

EmStat Pico Core

Based on ADuCM355

Works with MethodSCRIPT

Minimum Order Quantity




18 x 30 mm 

5 x 6 mm

1TΩ Input impedance


Extra current 100nA range


Calibration of external tia resistors

The optional items depend on the implementation of the PalmSens reference design.

Supported techniques

There are four different versions available, each with different electrochemical techniques: A, B, C and ALL. The default version is ALL, from 50+ units the A, B and C versions are available. 

Voltammetric techniques

Linear Sweep Voltammetry LSV
Cyclic Voltammetry CV
Square Wave Voltammetry SWV    
Differential Pulse Voltammetry DPV    
Normal Pulse Voltammetry NPV    

Techniques as a function of time

Chronoamperometry CA
Pulsed Amperometric Detection PAD
Open Circuit Potentiometry OCP
MultiStep Amperometry MA
Electrochemical Impedance Spectroscopy EIS    


The module works at three different modes;
Low Speed mode: for scan rates up to 1 V/s or a bandwidth of 100 Hz.
High Speed mode: for high scan rates and frequencies.
Max Range mode: a combination of the Low and High Speed modes for optimal dynamic dc-potential range.

  Low Speed mode High Speed mode Max Range mode
Full dc-potential range -1.2 to +2 V -1.7 to +2 V -1.7 to +2 V
Dynamic dc-potential range [1] 2.2 V 1.2 V 2.6 V
Compliance voltage -2.0 to +2.3 V [2]
Maximum current ± 3 mA
Max. acquisition rate
100 1000 100
Potentiostat (controlled potential mode)
Channels 2 (2x WE, 2x RE and 2x CE)
Applied dc-potential resolution 537 µV 395 µV 932 µV
Applied potential accuracy < 0.2% < 0.5% < 0.5%
Current ranges 100 nA, 2 uA,
4 uA, 8 uA,
16 uA, 32 uA,
63 uA, 125 uA,
250 uA, 500 uA,
1 mA, 5 mA
100 nA, 1 uA,
6 uA, 13 uA,
25 uA, 50 uA,
100 uA,
200 uA, 1 mA,
5 mA
100 nA, 1 uA,
6 uA, 13 uA,
25 uA, 50 uA,
100 uA,
200 uA, 1 mA,
5 mA
Current accuracy < 0.5 % of the selected current range
< 2% for 100 nA current range
< 1% of the selected current range
< 2% for 100 nA current range
< 2% for 5 mA current range
Measured current resolution 0.006% of selected current range
(5.5 pA on 100 nA range)
Measured potential resolution (for OCP) 56 uV
FRA / EIS (impedance measurements)
Frequency range 0.016 Hz to 200 kHz
Ac-amplitude range 1 mV to 0.25 V rms, or 0.708 V p-p
Modes 1. WE2 at fixed potential (E offset vs RE1)
2. WE2 scanning (E offset vs WE1)
Max. potential WE2 ΔE(WE1) + ΔE(WE2) < 1.6 V  [3]
Electrometer amplifier input > 1 TΩ // 10 pF
Bandwidth  250 kHz
Communications and peripherals
Module communication UART
Communication with external peripherals SPI and I2C
Analog I/O 3 analog input pins
Digital I/O 7 general-purpose I/O pins
1 wake-up pin
On-board temperature sensor ±2 °C or ±0.25 °C [4]
Storage 4000 datapoints on-board (supports optional external SD card or NAND chip for mass storage)
Mounting 72-lead LGA package
Dimensions 5 mm X 6 mm 
Operation temperature range -40°C to +85°C

[1]  The dynamic range is the range that can be covered during a single scan within the full potential range. For example; a linear scan can start at -1.5 V and end at 1.1 V or vice versa, covering 2.6 V dynamic range.
[2] The compliance voltage is the maximum potential between Working and Counter electrode and depends on the selected mode.
[3] If your main WE1 is scanning from -0.5V to +0.5V, the WE2 can only have a maximum offset of 0.6V.
[4] The high accurate on-board temperature sensor is standard available on modules that come with the EmStat Pico Development Kit. For separate EmStat Pico modules the temperature sensor is optional.

Dual-channel and Bipotentiostat functionality

The second channel of the EmStat Pico can be used for running sequential measurements on two different cells each with their own Reference, Counter and Working electrodes.
The second channel can also be used in Bipotentiostat mode, functioning as second Working Electrode versus the Reference and Counter electrode of channel 1. Both channels are recorded simultaneously in the Bipotentiostat mode.

The second Working Electrode (WE2) can either be set at a potential offset with respect to WE1 or at a fixed potential with respect to RE1.

The Bipotentiostat mode is supported in Low Speed mode (see table above) for all techniques, excluding EIS and OCP.

EIS Accuracy Contour Plot

Read more


Develop software for PC, smartphone or microcontroller

Whether you want to write a simple or advanced Windows application, develop an Android or iPhone app or integrate the EmStat Pico in your own hardware, you can do it with our software development tools and code examples.

The EmStat Pico Development Board can also be controlled directly with our PSTrace software for Windows and PStouch app for Android.

Overview of software development tools

Software Development Kits for .NET

The PalmSens Software Development Kits (SDKs) for .NET can be used with any of our instruments or OEM potentiostat modules to develop your own software. The SDK’s come with a set of examples that shows how to use the libraries.

PalmSens SDKs with examples are available for the following .NET Frameworks:

  • WinForms
  • WPF
  • Xamarin (for Android)
  • UWP

SDKs for .NET

MethodSCRIPT™ communications protocol

The EmStat Pico potentiostat module has an on-board parser for the MethodSCRIPT scripting language. This language allows developers to program a human-readable script for the EmStat Pico module on any platform or operating system. The simple script language allows for running electrochemical techniques supported by EmStat Pico and makes it easy to combine different measurements and other tasks.

More information about MethodSCRIPT


Name Type Last updated
Introduction to electrochemical sensing – Tutorial The first part of this presentation contains how electrochemistry works and how it can be used for sensing applications. The second half explains what a potentiostat is and which applications are suitable for the EmStat Pico potentiostat offered by PalmSens. Details of the EmStat Pico’s capabilities will be shown, as well as instructions on how to use it.other15-07-21
Limitations for EIS on EmStat Pico application-note18-12-20
pH Measurement using EmStat Pico This article shows the ease of integration of the device into a system and demonstrates the range of applications of the potentiostat module by detailing three different electrochemical measurements: OCP (pH), cyclic voltammetry, and EIS.application-note07-09-20
MethodSCRIPT v1.2 protocol description MethodSCRIPT v1.2 protocol descriptiondocumentation28-04-20
EmStat Pico communication protocol v1.2 Describes the EmStat Pico communications protocol which is based on MethodSCRIPTdocumentation08-04-20
MethodSCRIPT code examples MethodSCRIPT code examples include:
- MethodSCRIPTExample_C
- MethodSCRIPTExample_C_Linux
- MethodSCRIPTExample_C#
- MethodSCRIPTExample_Arduino
- MethodSCRIPTExample_Python
- MethodSCRIPTExample_iOS
- MethodSCRIPTExample_Android
Every code example comes with a "Getting Started" document.
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